Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000385 | 0.88 | ALDH1A1 (0.40) | ACHEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3999096 | 0.88 | ACHE (0.41) | ACHEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4007026 | 0.87 | ACHE (0.40) | ACHEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4000459 | 0.86 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3011145 | 0.82 | ACHE (0.49) | ACHEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4003846 | 0.82 | ACHE (0.43) | ACHEGAAALDH1A1ALOX12MAPT | |
| SCHEMBL4001686 | 0.82 | MAPT (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3010624 | 0.81 | ACHE (0.47) | ACHEKMT2AGAAALDH1A1ALOX12 | |
| SCHEMBL4002142 | 0.81 | KMT2A (0.44) | ACHEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4002432 | 0.80 | ALDH1A1 (0.40) | ACHEMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |