Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3013804 | 0.89 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1LMNAUSP2 | |
| SCHEMBL4003846 | 0.89 | ACHE (0.43) | ALDH1A1GAAACHEBCHE | |
| SCHEMBL4003793 | 0.86 | CSNK2A2 (0.42) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL4005421 | 0.85 | CSNK2A2 (0.41) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL3013194 | 0.85 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1LMNAUSP2 | |
| SCHEMBL4000385 | 0.81 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1LMNAUSP2 | |
| SCHEMBL3011145 | 0.80 | ACHE (0.49) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL3998431 | 0.80 | LMNA (0.40) | GRIN1GRIN2BGRIN2DGRIN3BADRA1A | |
| SCHEMBL3001735 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL3001985 | 0.78 | CSNK2A2 (0.43) | MEN1KMT2AALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |