Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | BCL9 | O00512 | 3/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005421 | 0.91 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1SMN1; SMN2MAPT | |
| SCHEMBL4003846 | 0.89 | ACHE (0.43) | CSNK2A2CSNK2BCSNK2A1MAPTALDH1A1 | |
| SCHEMBL3010725 | 0.88 | HTT (0.53) | CSNK2A2CSNK2BCSNK2A1SMN1; SMN2MAPT | |
| SCHEMBL4000382 | 0.86 | GRIN1 (0.48) | HTTALDH1A1MEN1LMNAHPGD | |
| SCHEMBL3009750 | 0.83 | FKBP1A (0.47) | CSNK2A2CSNK2BCSNK2A1SMN1; SMN2MAPT | |
| SCHEMBL3001735 | 0.83 | ALDH1A1 (0.55) | CSNK2A2CSNK2BCSNK2A1SMN1; SMN2MAPT | |
| SCHEMBL3002368 | 0.82 | CSNK2A2 (0.48) | CSNK2A2CSNK2BCSNK2A1SMN1; SMN2MAPT | |
| SCHEMBL3001522 | 0.82 | CSNK2A2 (0.48) | CSNK2A2CSNK2BCSNK2A1SMN1; SMN2MAPT | |
| SCHEMBL3006035 | 0.82 | CSNK2A2 (0.43) | CSNK2A2CSNK2BCSNK2A1SMN1; SMN2MAPT | |
| SCHEMBL3001825 | 0.81 | MAPT (0.43) | CSNK2A2CSNK2BCSNK2A1SMN1; SMN2BCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |