Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3011145 | 0.91 | ACHE (0.49) | ACHEALDH1A1GAAKDM4EALOX12 | |
| SCHEMBL4000382 | 0.89 | GRIN1 (0.48) | ACHEALDH1A1GAABCHE | |
| SCHEMBL4003793 | 0.89 | CSNK2A2 (0.42) | ALDH1A1GAAMAPTKDM4ECSNK2A2 | |
| SCHEMBL4005421 | 0.88 | CSNK2A2 (0.41) | ALDH1A1GAAMAPTKDM4ESIGMAR1 | |
| SCHEMBL3010624 | 0.86 | ACHE (0.47) | ACHEHTR1AHTR7HTR6ALDH1A1 | |
| SCHEMBL3014065 | 0.84 | ALDH1A1 (0.50) | HTR1AHTR7HTR6ALDH1A1GAA | |
| SCHEMBL4003849 | 0.82 | ACHE (0.41) | ACHEALDH1A1GAAMAPTKDM4E | |
| SCHEMBL3001735 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTKDM4ECSNK2A2 | |
| SCHEMBL3001985 | 0.81 | CSNK2A2 (0.43) | ALDH1A1GAAMAPTKDM4ECSNK2A2 | |
| SCHEMBL3999096 | 0.81 | ACHE (0.41) | ACHEHTR1AHTR7HTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |