Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003862 | 0.93 | KMT2A (0.42) | ACHEMEN1KMT2AHTR1AHTR7 | |
| SCHEMBL3999096 | 0.90 | ACHE (0.41) | ACHETHRBMEN1KMT2AHTR1A | |
| SCHEMBL4003849 | 0.87 | ACHE (0.41) | ACHETHRBMEN1KMT2AGAA | |
| SCHEMBL4002142 | 0.82 | KMT2A (0.44) | ACHEMEN1KMT2AHTR1AHTR7 | |
| SCHEMBL3011145 | 0.79 | ACHE (0.49) | ACHEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4003846 | 0.79 | ACHE (0.43) | ACHETHRBHTR1AHTR7HTR6 | |
| SCHEMBL3010624 | 0.78 | ACHE (0.47) | ACHEKMT2AHTR1AHTR7HTR6 | |
| SCHEMBL3998431 | 0.78 | LMNA (0.40) | THRBMEN1KMT2AHTR1AHTR7 | |
| SCHEMBL4007345 | 0.76 | MEN1 (0.38) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4000385 | 0.75 | ALDH1A1 (0.40) | ACHEMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | claimed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | claimed |