SCHEMBL4006072

SCHEMBL4006072

C=CC1CC12COC(=O)OC2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5538369 0.66
SCHEMBL5537573 0.66 NR1I2 (0.30) NR1I2
SCHEMBL732557 0.65 NR1I2 (0.31) NR1I2
SCHEMBL16212625 0.62
SCHEMBL5536035 0.62 GABRP (0.34)
SCHEMBL28573642 0.61
SCHEMBL734755 0.61 PRSS1 (0.34) NR1I2
SCHEMBL10064389 0.60 NR1I2 (0.32) NR1I2
SCHEMBL8776615 0.60 PRKCA (0.33)
SCHEMBL10064390 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7118258-A None JP disclosed
US-11135136-B2 Dental materials based on urethane-group-containing vinylcyclopropane derivatives IVOCLAR VIVADENT AG (LI) 2021-10-05 US disclosed
US-10660825-B2 2020-05-26 US disclosed
US-20190167533-A1 DENTAL MATERIALS BASED ON URETHANE-GROUP-CONTAINING VINYLCYCLOPROPANE DERIVATIVES IVOCLAR VIVADENT AG (LI) 2019-06-06 US disclosed
EP-3278786-B1 DENTAL MATERIALS ON THE BASIS OF VINYLCYCLOPROPANE DERIVATIVES CONTAINING URETHANE GROUPS IVOCLAR VIVADENT AG (LI) 2019-01-23 EP disclosed
US-20180036209-A1 Dental Materials Based on Monofunctional Vinylcyclopropane Derivatives IVOCLAR VIVADENT AG (LI) 2018-02-08 US disclosed
US-9595734-B2 Non-aqueous liquid electrolyte for secondary battery and secondary battery FUJIFILM CORPORATION (JP) 2017-03-14 US disclosed
US-9595734-B2 Non-aqueous liquid electrolyte for secondary battery and secondary battery FUJIFILM CORPORATION (JP) 2017-03-14 US disclosed
US-20140234729-A1 NON-AQUEOUS LIQUID ELECTROLYTE FOR SECONDARY BATTERY AND SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2014-08-21 US disclosed
US-20140234729-A1 NON-AQUEOUS LIQUID ELECTROLYTE FOR SECONDARY BATTERY AND SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2014-08-21 US disclosed
US-7585901-B2 Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials IVOCLAR VIVADENT AG (LI) 2009-09-08 US disclosed
US-7365222-B2 1,1-Disubstituted 2-vinylcyclopropanes; free radical polymerizable monomers IVOCLAR VIVADENT AG (LI) 2008-04-29 US disclosed
US-20070232719-A1 POLYMERIZABLE BICYCLIC CYCLOPROPANE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF DENTAL MATERIALS IVOCLAR VIVADENT AG (LI) 2007-10-04 US disclosed
EP-1413569-B1 Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials IVOCLAR VIVADENT AG (LI) 2006-12-13 EP disclosed
EP-1413569-A1 Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials Ivoclar Vivadent AG (LI) 2004-04-28 EP disclosed
US-20040077882-A1 Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials IVOCLAR VIVADENT AG (LI) 2004-04-22 US disclosed
EP-0943601-B1 Vinylcyclopropane-(meth)acrylates as well as their use IVOCLAR VIVADENT AG (LI) 2003-05-02 EP disclosed
US-6136887-A Vinylcyclopropane-(meth)acrylates and their use IVOCLAR AG (LI) 2000-10-24 US disclosed
EP-0943601-A1 Vinylcyclopropane-(meth)acrylates as well as their use IVOCLAR AG (LI) 1999-09-22 EP disclosed
JP-H07118258-A CYCLIC CARBONATE-CONTAINING VINYLCYCLOPROPANE COMPOUND AND POLYMER OBTAINED FROM THE SAME KURARAY CO LTD 1995-05-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232719-A1 POLYMERIZABLE BICYCLIC CYCLOPROPANE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF DENTAL MATERIALS CBR1, CYP8B1, OXER1 NR1I2 108/4885
US-20180036209-A1 Dental Materials Based on Monofunctional Vinylcyclopropane Derivatives HVCN1, RAD51, HYOU1 NR1I2 337/4885
US-20190167533-A1 DENTAL MATERIALS BASED ON URETHANE-GROUP-CONTAINING VINYLCYCLOPROPANE DERIVATIVES RAD51, CBR1, DECR1 NR1I2 81/4885
US-20040077882-A1 Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials SCO2, CBR1, CORO1C NR1I2 255/4885
US-11135136-B2 Dental materials based on urethane-group-containing vinylcyclopropane derivatives RAD51, CBR1, DECR1 NR1I2 81/4885
US-10660825-B2 OXER1, CBR1, RAD51 NR1I2 152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.