Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996952 | 0.89 | MAOB (0.47) | SLC6A2SLC6A3SLC6A4MAOBMAPT | |
| SCHEMBL872275 | 0.84 | SLC6A4 (0.62) | SLC6A2SLC6A3SLC6A4MAPT | |
| SCHEMBL878028 | 0.81 | SLC6A2 (0.54) | SLC6A2SLC6A3SLC6A4LTA4HLMNA | |
| SCHEMBL6210983 | 0.81 | DPP4 (0.57) | SLC6A2SLC6A3SLC6A4MAOBGAA | |
| SCHEMBL15065610 | 0.78 | SLC6A4 (0.49) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL6210261 | 0.78 | DPP4 (0.62) | SLC6A2SLC6A3SLC6A4MAOBGAA | |
| SCHEMBL6502368 | 0.77 | SLC6A3 (0.60) | SLC6A2SLC6A3SLC6A4MAOBGAA | |
| SCHEMBL8606048 | 0.75 | SLC6A3 (0.53) | SLC6A2SLC6A3SLC6A4MAPTLMNA | |
| SCHEMBL871578 | 0.75 | SLC6A3 (0.53) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL871941 | 0.75 | SLC6A3 (0.53) | SLC6A2SLC6A3SLC6A4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066329-A2 | SYNTHESIS, METHODS OF USING, AND COMPOSITIONS OF CYCLOALKYLMETHYLAMINES | Reviva Pharmaceuticals, Inc. (US) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008034142-A2 | SYNTHESIS, METHODS OF USING, AND COMPOSITIONS OF CYCLOALKYLMETHYLAMINES | REVIVA PHARMACEUTICALS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |