Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.62 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878028 | 0.90 | SLC6A2 (0.54) | SLC6A4SLC6A2SLC6A3TSHRCA12 | |
| SCHEMBL4006943 | 0.84 | SLC6A2 (0.47) | SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL15065610 | 0.83 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3996952 | 0.83 | MAOB (0.47) | SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL871578 | 0.80 | SLC6A3 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8606048 | 0.80 | SLC6A3 (0.53) | SLC6A4SLC6A2SLC6A3TSHRMAPT | |
| SCHEMBL8040636 | 0.80 | SLC6A3 (0.53) | SLC6A4SLC6A2SLC6A3TSHRMAPT | |
| SCHEMBL871941 | 0.80 | SLC6A3 (0.53) | SLC6A4SLC6A2SLC6A3TSHRMAPT | |
| SCHEMBL15066384 | 0.79 | SLC6A2 (0.69) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL15065699 | 0.79 | SLC6A2 (0.69) | SLC6A4SLC6A2SLC6A3NQO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797870-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | Reviva Pharmaceuticals, Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013102195-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |
| WO-2012003501-A2 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING CYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |