Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.38 |
| ▸ | PGR | P06401 | 4/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011760 | 0.84 | NR3C1 (0.38) | NR3C1PGRTRPA1AR | |
| SCHEMBL4008930 | 0.74 | SCN9A (0.36) | NR3C1PGRAR | |
| SCHEMBL4008243 | 0.73 | ITK (0.48) | TRPA1 | |
| SCHEMBL4008403 | 0.69 | KDM4E (0.42) | NR3C1PGR | |
| SCHEMBL4008240 | 0.68 | TRPA1 (0.49) | TRPA1 | |
| SCHEMBL5635166 | 0.67 | CYP11B1 (0.40) | — | |
| SCHEMBL4010508 | 0.64 | — | — | |
| SCHEMBL4009389 | 0.61 | CDC7 (0.44) | TRPA1 | |
| SCHEMBL9818427 | 0.59 | KDR (0.54) | — | |
| SCHEMBL9507935 | 0.57 | GSTP1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473701-B2 | Substituted indazoles, compositions containing them, method of production and use | AVENTIS PHARMA S.A. (FR) | 2009-01-06 | — | — | US | claimed |