Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 15/20 | 0.34 |
| ▸ | PGR | P06401 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 4/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011760 | 0.80 | NR3C1 (0.38) | SCN9ANR3C1PGRAR | |
| SCHEMBL4008236 | 0.74 | NR3C1 (0.38) | NR3C1PGRAR | |
| SCHEMBL4008940 | 0.70 | ITK (0.50) | FGFR1KDR | |
| SCHEMBL5635166 | 0.70 | CYP11B1 (0.40) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL4010508 | 0.66 | — | — | |
| SCHEMBL4008937 | 0.65 | TRPA1 (0.48) | FGFR1 | |
| SCHEMBL516901 | 0.55 | CA2 (0.67) | — | |
| SCHEMBL29560278 | 0.55 | CA2 (0.67) | — | |
| SCHEMBL30066459 | 0.55 | MAPK14 (0.42) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL28173303 | 0.55 | GSTP1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473701-B2 | Substituted indazoles, compositions containing them, method of production and use | AVENTIS PHARMA S.A. (FR) | 2009-01-06 | — | — | US | claimed |