Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007180 | 0.86 | TRPA1 (0.57) | HTR1ASLC6A2SLC6A4TRPA1SLC6A3 | |
| SCHEMBL4009097 | 0.82 | TRPA1 (0.52) | HTR1ASLC6A2SLC6A4TRPA1SLC6A3 | |
| SCHEMBL4006188 | 0.82 | HTR1A (0.42) | HTR1ASLC6A2SLC6A4PRKAG1PRKAA1 | |
| SCHEMBL20406236 | 0.80 | HTR1A (0.39) | HTR1ASLC6A2SLC6A4TRPA1SLC6A3 | |
| SCHEMBL20406235 | 0.79 | MAPT (0.47) | HTR1ASLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL4008185 | 0.77 | PDE10A (0.44) | HTR1ASLC6A2SLC6A4TRPA1SLC6A3 | |
| SCHEMBL7910614 | 0.76 | KMT2A (0.59) | MAPTKDM4EDRD1L3MBTL1POLB | |
| SCHEMBL28115709 | 0.75 | HTR1A (0.49) | HTR1ASLC6A2SLC6A4TRPA1KDM4E | |
| SCHEMBL4008138 | 0.75 | HTR1A (0.54) | HTR1ASLC6A2SLC6A4TRPA1SLC6A3 | |
| SCHEMBL4012114 | 0.75 | TRPA1 (0.49) | HTR1ASLC6A2SLC6A4TRPA1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |