Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011472 | 0.89 | MAPT (0.39) | ADORA3NPC1RAB9AATMNPSR1 | |
| SCHEMBL4011273 | 0.89 | ADORA3 (0.38) | DPP4DPP9DPP8ADORA3ADORA1 | |
| SCHEMBL4011136 | 0.86 | RAB9A (0.38) | HTTRAB9ANPSR1MAPTPRNP | |
| SCHEMBL4009025 | 0.82 | ACP1 (0.38) | ADORA3ADORA1NPC1MAPTTSHR | |
| SCHEMBL4010057 | 0.81 | DPP4 (0.48) | DPP4DPP9DPP8ADORA3ADORA1 | |
| SCHEMBL4009391 | 0.80 | ALDH1A1 (0.41) | DPP4DPP9ADORA3ADORA1HTT | |
| SCHEMBL4007725 | 0.78 | ADORA3 (0.39) | ADORA3NPC1HTTRAB9ANPSR1 | |
| SCHEMBL4005144 | 0.78 | PPARA (0.39) | ADORA3NPC1RAB9AMAPTGABRA2 | |
| SCHEMBL4010068 | 0.78 | PPARG (0.40) | ADORA3RAB9AATMNPSR1MAPT | |
| SCHEMBL8038540 | 0.78 | GCGR (0.45) | DPP4DPP9DPP8ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |