Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011568 | 0.83 | FABP4 (0.42) | PDE4BPDE4DTDP1L3MBTL1ADORA3 | |
| SCHEMBL8031870 | 0.80 | SLC6A3 (0.42) | PDE4BPDE4DL3MBTL1CNR1ADORA3 | |
| SCHEMBL4006533 | 0.80 | PDE4B (0.39) | PDE4BPDE4DL3MBTL1ADORA3ALDH1A1 | |
| SCHEMBL4009408 | 0.78 | DHPS (0.39) | PDE4BPDE4DCNR1ADORA3SMN1; SMN2 | |
| SCHEMBL4151852 | 0.77 | ADORA3 (0.44) | ADORA3ADORA1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL4011472 | 0.77 | MAPT (0.39) | TDP1ADORA3RXRANR4A2SMN1; SMN2 | |
| SCHEMBL4007862 | 0.77 | NAMPT (0.38) | PDE4DTDP1ADORA3RXRANR4A2 | |
| SCHEMBL4005144 | 0.76 | PPARA (0.39) | PDE4DTDP1ADORA3RXRANR4A2 | |
| SCHEMBL4008876 | 0.76 | ATM (0.48) | PDE4BPDE4DCNR1ADORA3SMN1; SMN2 | |
| SCHEMBL4009793 | 0.75 | NR1H4 (0.37) | PDE4BPDE4DCNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |