Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4360071 | 0.81 | TSHR (0.45) | L3MBTL1ALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL6640962 | 0.80 | TSHR (0.53) | ALDH1A1PBRM1LMNATSHRMEN1 | |
| SCHEMBL10386798 | 0.79 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1PBRM1LMNASMN1; SMN2 | |
| SCHEMBL5455142 | 0.79 | ALDH1A1 (0.61) | L3MBTL1ALDH1A1TP53HTTTSHR | |
| SCHEMBL27853749 | 0.78 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1GAAPBRM1TSHR | |
| SCHEMBL28214418 | 0.78 | THRB (0.45) | ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL11327561 | 0.76 | HMGB1 (0.54) | L3MBTL1ALDH1A1TP53HTTTSHR | |
| SCHEMBL23708 | 0.76 | FOLH1 (0.50) | ALDH1A1SMN1; SMN2TSHRNR4A2FOLH1 | |
| SCHEMBL31090800 | 0.76 | FOLH1 (0.50) | ALDH1A1SMN1; SMN2TSHRNR4A2FOLH1 | |
| SCHEMBL29367715 | 0.76 | FOLH1 (0.50) | ALDH1A1SMN1; SMN2TSHRNR4A2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080744-A1 | CRYSTALLINE FORM OF AZELASTINE | Esteve Química, S.A. (ES) | 2009-07-02 | — | — | WO | disclosed |