Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | LDHB | P07195 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010438 | 0.81 | L3MBTL1 (0.46) | TSHRALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL4905340 | 0.78 | TSHR (0.72) | TSHRNR4A1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4844133 | 0.77 | TSHR (0.53) | TSHRNR4A1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL200212 | 0.76 | TSHR (0.59) | TSHRALDH1A1PTPN1FOLH1 | |
| SCHEMBL7781040 | 0.76 | TSHR (0.51) | TSHRNR4A1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL343520 | 0.74 | TSHR (0.57) | TSHRALDH1A1PTPN1FOLH1 | |
| SCHEMBL31258255 | 0.74 | L3MBTL1 (0.54) | TSHRALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28094825 | 0.73 | PTPN1 (0.43) | TSHRALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28214418 | 0.73 | THRB (0.45) | ALDH1A1CYP2C9LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL598165 | 0.73 | CA12 (0.48) | TSHRNR4A1ALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072510-A1 | Crystalline form of azelastine | ESTEVE QUIMICA, S.A. (ES) | 2009-06-24 | — | — | EP | disclosed |