Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005701 | 0.88 | CXCR2 (0.36) | EPHX2GAAKMT2AHPGDMEN1 | |
| SCHEMBL4004677 | 0.83 | KMT2A (0.47) | EPHX2GAAKMT2AHDAC3HDAC1 | |
| SCHEMBL4004804 | 0.83 | KMT2A (0.47) | EPHX2GAAKMT2AHDAC3HDAC1 | |
| SCHEMBL4005033 | 0.83 | EPHX2 (0.35) | EPHX2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL4010821 | 0.81 | KMT2A (0.37) | EPHX2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL4009267 | 0.80 | HSD11B1 (0.39) | EPHX2GAAKMT2AMEN1LMNA | |
| SCHEMBL4292846 | 0.80 | EPHX2 (0.45) | EPHX2 | |
| SCHEMBL4002524 | 0.80 | EPHX2 (0.48) | EPHX2GAAKMT2AMEN1LMNA | |
| SCHEMBL4009421 | 0.80 | CNR1 (0.48) | KMT2ALMNAALDH1A1RXFP1 | |
| SCHEMBL4306301 | 0.80 | EPHX2 (0.43) | EPHX2KMT2AHPGDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |