Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 6/20 | 0.43 |
| ▸ | HTR6 | P50406 | 12/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005033 | 0.83 | EPHX2 (0.35) | EPHX2 | |
| SCHEMBL4010678 | 0.83 | HSD11B1 (0.45) | EPHX2 | |
| SCHEMBL4006938 | 0.83 | L3MBTL1 (0.39) | EPHX2 | |
| SCHEMBL4001806 | 0.83 | ATM (0.44) | EPHX2 | |
| SCHEMBL4006999 | 0.82 | EPHX2 (0.47) | EPHX2 | |
| SCHEMBL4010824 | 0.82 | EIF2AK3 (0.46) | — | |
| SCHEMBL4006571 | 0.82 | HSD11B1 (0.43) | — | |
| SCHEMBL4009618 | 0.81 | PKM (0.40) | EPHX2 | |
| SCHEMBL4005701 | 0.81 | CXCR2 (0.36) | EPHX2 | |
| SCHEMBL4003470 | 0.81 | CTSS (0.39) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |