Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17188052 | 0.90 | HTR2A (0.50) | SLC6A9SSTR4HTR2AHSD17B10AKR1C1 | |
| SCHEMBL4010839 | 0.83 | SLC6A9 (0.51) | SLC6A9SSTR4TACR3 | |
| SCHEMBL2712662 | 0.83 | SSTR4 (0.53) | SSTR4HSD17B10TACR3AKR1C1HDAC4 | |
| SCHEMBL3560390 | 0.83 | SSTR4 (0.56) | SSTR4HSD17B10TACR3AKR1C1HDAC4 | |
| SCHEMBL4007365 | 0.82 | SSTR4 (0.54) | SLC6A9SSTR4OPRM1HDAC3HDAC1 | |
| SCHEMBL4006927 | 0.82 | SLC6A9 (0.49) | SLC6A9SSTR4HSD17B10TACR3HDAC1 | |
| SCHEMBL4006087 | 0.82 | SSTR4 (0.54) | SLC6A9SSTR4OPRM1HDAC3HDAC1 | |
| SCHEMBL6972395 | 0.81 | OPRM1 (0.50) | SSTR4HTR2AHSD17B10TACR3AKR1C1 | |
| SCHEMBL6620132 | 0.81 | SSTR4 (0.59) | SSTR4TACR3AKR1C1HDAC4HDAC3 | |
| Hydrochloric Acid SCHEMBL7723494 | 0.80 | OPRM1 (0.48) | SSTR4HTR2AHSD17B10TACR3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |