Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009940 | 0.86 | SLC6A9 (0.52) | SLC6A9P2RX7TACR3SSTR4 | |
| SCHEMBL4011286 | 0.83 | SLC6A9 (0.50) | SLC6A9TACR3SSTR4 | |
| SCHEMBL4004238 | 0.79 | TACR3 (0.48) | SLC6A9TACR3RAB9A | |
| SCHEMBL4006927 | 0.78 | SLC6A9 (0.49) | SLC6A9HPGDTACR3SSTR4NPC1 | |
| SCHEMBL4006834 | 0.77 | SLC6A9 (0.56) | SLC6A9NPC1RAB9AKDM4E | |
| SCHEMBL4000824 | 0.75 | SLC6A9 (0.49) | SLC6A9HPGDSSTR4NPC1RAB9A | |
| SCHEMBL17188052 | 0.74 | HTR2A (0.50) | SLC6A9HPGDSSTR4KDM4E | |
| SCHEMBL4003575 | 0.74 | ALDH1A1 (0.58) | SLC6A9NPC1RAB9A | |
| SCHEMBL4006087 | 0.73 | SSTR4 (0.54) | SLC6A9HPGDSSTR4NPC1RAB9A | |
| SCHEMBL4007365 | 0.73 | SSTR4 (0.54) | SLC6A9HPGDSSTR4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | claimed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | claimed |
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |