Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC33A1 | O00400 | 14/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892460 | 0.90 | SLC33A1 (0.41) | SLC33A1PPARGKDM4EALDH1A1GAA | |
| SCHEMBL4010015 | 0.83 | PPARG (0.38) | SLC33A1PPARGTSHRFFAR1AKR1B1 | |
| SCHEMBL4319356 | 0.82 | ACHE (0.38) | SLC33A1PPARGFFAR1AKR1B1 | |
| SCHEMBL4306949 | 0.80 | ACHE (0.40) | SLC33A1PPARGFFAR1AKR1B1 | |
| SCHEMBL1894521 | 0.80 | SLC33A1 (0.40) | SLC33A1PPARG | |
| SCHEMBL1891360 | 0.79 | HRH3 (0.43) | SLC33A1PPARG | |
| SCHEMBL1890836 | 0.77 | SLC33A1 (0.37) | SLC33A1PPARG | |
| SCHEMBL1892653 | 0.77 | HRH3 (0.42) | SLC33A1 | |
| SCHEMBL4009738 | 0.76 | AGTR1 (0.37) | SLC33A1PPARGFFAR1AKR1B1 | |
| SCHEMBL1890120 | 0.76 | HRH3 (0.42) | SLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |