Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | SLC33A1 | O00400 | 10/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306949 | 0.92 | ACHE (0.40) | ACHEPPARGSLC33A1FFAR1AKR1B1 | |
| SCHEMBL1885478 | 0.90 | ACHE (0.37) | ACHEPPARGSLC33A1FFAR1AKR1B1 | |
| SCHEMBL4010015 | 0.83 | PPARG (0.38) | PPARGSLC33A1FFAR1AKR1B1AGTR1 | |
| SCHEMBL1896768 | 0.83 | ACHE (0.39) | ACHEPPARGSLC33A1FFAR1AKR1B1 | |
| SCHEMBL4012069 | 0.82 | SLC33A1 (0.43) | PPARGSLC33A1FFAR1AKR1B1 | |
| SCHEMBL13341905 | 0.79 | ACHE (0.39) | ACHEPPARGFFAR1AKR1B1AGTR1 | |
| SCHEMBL12349035 | 0.79 | ACHE (0.40) | ACHEPPARGFFAR1AKR1B1AGTR1 | |
| SCHEMBL1890208 | 0.77 | ACHE (0.42) | ACHEPPARGFFAR1AKR1B1AGTR1 | |
| SCHEMBL4009738 | 0.77 | AGTR1 (0.37) | ACHEPPARGSLC33A1FFAR1AKR1B1 | |
| SCHEMBL13368435 | 0.77 | ACHE (0.38) | ACHEPPARGSLC33A1AGTR1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |