Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | PRLHR | P49683 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23352280 | 0.82 | ALDH1A1 (0.40) | KMT2ASMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL21612764 | 0.81 | L3MBTL1 (0.40) | KMT2ALMNAHTTALDH1A1GAA | |
| SCHEMBL31018181 | 0.81 | L3MBTL1 (0.40) | KMT2ALMNAHTTALDH1A1GAA | |
| SCHEMBL4012243 | 0.81 | GPBAR1 (0.50) | PRLHRGPBAR1 | |
| SCHEMBL31018194 | 0.80 | PRLHR (0.38) | KMT2ASMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL21612758 | 0.80 | PRLHR (0.38) | KMT2ASMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL13962556 | 0.79 | GPBAR1 (0.45) | GPBAR1 | |
| SCHEMBL3099388 | 0.77 | TRPV1 (0.39) | KMT2ALMNAHTTGAAPRLHR | |
| SCHEMBL31018186 | 0.77 | TRPV1 (0.39) | KMT2ALMNAHTTGAAPRLHR | |
| SCHEMBL3099369 | 0.77 | TRPV1 (0.39) | KMT2ALMNAHTTGAAPRLHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112437771-B | Bronchodilating heteroatom-linked amides | 阿凯德制药公司 | 2024-06-18 | — | — | CN | disclosed |
| US-11680054-B2 | Bronchodilating hetero-linked amides | ARCEDE PHARMA AB (SE) | 2023-06-20 | — | — | US | disclosed |
| US-11680054-B2 | Bronchodilating hetero-linked amides | ARCEDE PHARMA AB (SE) | 2023-06-20 | — | — | US | disclosed |
| US-11680054-B2 | Bronchodilating hetero-linked amides | ARCEDE PHARMA AB (SE) | 2023-06-20 | — | — | US | disclosed |
| EP-3818055-B1 | NOVEL BRONCHODILATING HETERO-LINKED AMIDES | RESPIRATORIUS AB PUBL (SE) | 2022-02-16 | — | — | EP | disclosed |
| EP-3818055-B1 | NOVEL BRONCHODILATING HETERO-LINKED AMIDES | RESPIRATORIUS AB PUBL (SE) | 2022-02-16 | — | — | EP | disclosed |
| US-20210139455-A1 | NOVEL BRONCHODILATING HETERO-LINKED AMIDES | ARCEDE PHARMA AB (SE) | 2021-05-13 | — | — | US | disclosed |
| US-20210139455-A1 | NOVEL BRONCHODILATING HETERO-LINKED AMIDES | ARCEDE PHARMA AB (SE) | 2021-05-13 | — | — | US | disclosed |
| WO-2020009653-A1 | NOVEL BRONCHODILATING HETERO-LINKED AMIDES | RESPIRATORIUS AB (PUBL) (SE) | 2020-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11680054-B2 | Bronchodilating hetero-linked amides | PTGIS, PTGIR, ADRB2 | KMT2A 3773/4885SMN1; SMN2 4854/4885LMNA 4127/4885 |
| US-20210139455-A1 | NOVEL BRONCHODILATING HETERO-LINKED AMIDES | ADRB2, ADRB1, PTGIS | KMT2A 3368/4885SMN1; SMN2 4870/4885LMNA 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.