Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054313 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAAHSD17B10DRD2NPC1 | |
| SCHEMBL8233359 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAAHSD17B10DRD2NPC1 | |
| SCHEMBL15299815 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HSD17B10NPC1TNFRAB9A | |
| SCHEMBL533931 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10DRD2NPC1 | |
| SCHEMBL2378357 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10DRD2NPC1 | |
| SCHEMBL14406750 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10DRD2NPC1 | |
| SCHEMBL1127911 | 0.80 | HTR6 (0.51) | ALDH1A1GAAHSD17B10DRD2GRM2 | |
| SCHEMBL7049486 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10DRD2NPC1 | |
| SCHEMBL2542290 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10DRD2NPC1 | |
| SCHEMBL29411715 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10DRD2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493439-B1 | Proteasome inhibitors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2016-11-15 | — | — | US | disclosed |
| US-8216975-B2 | Method of labelling soya varieties | Syngenta Crop Protection Inc (US) | 2012-07-10 | — | — | US | disclosed |
| US-8097774-B2 | Cytochrome P450 genes conferring herbicide resistance | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-17 | — | — | US | disclosed |
| US-20100305095-A1 | Use of HPPD Inhibitors in the Treatment of Depression and/or Withdrawal Symptoms Associated with Addictive Drugs | SYNGENTA LIMITED (GB) | 2010-12-02 | — | — | US | disclosed |
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| US-20090011936-A1 | Cytochrome P450 genes conferring herbicide resistance | SYNGENTA PARTICIPATIONS AG | 2009-01-08 | — | — | US | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305095-A1 | Use of HPPD Inhibitors in the Treatment of Depression and/or Withdrawal Symptoms Associated with Addictive Drugs | HPD, PGD, PEPD | ALDH1A1 63/4885GAA 130/4885HSD17B10 269/4885 |
| US-20090011936-A1 | Cytochrome P450 genes conferring herbicide resistance | HPD, DDT, ATP5PD | ALDH1A1 473/4885GAA 321/4885HSD17B10 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.