Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | PTPRF | P10586 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPA | Q15257 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934240 | 0.84 | LMNA (0.67) | GSTO1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4010031 | 0.80 | ALDH1A1 (0.57) | GSTO1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23599197 | 0.78 | LMNA (0.74) | GSTO1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23580345 | 0.77 | LMNA (0.73) | GSTO1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11634946 | 0.76 | LMNA (0.74) | GSTO1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2897094 | 0.75 | POLB (0.74) | GSTO1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21248147 | 0.75 | POLB (0.51) | GSTO1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6311362 | 0.74 | LMNA (0.71) | GSTO1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9396589 | 0.74 | LMNA (0.79) | GSTO1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27815398 | 0.73 | CASP3 (0.56) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011850-A2 | NOVEL THERAPEUTIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2009-01-22 | — | — | WO | disclosed |