Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | DHPS | P49366 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008876 | 0.90 | ATM (0.48) | ATMCNR1SLC6A3PDE4BPDE4D | |
| SCHEMBL4014601 | 0.84 | DHPS (0.42) | CNR1SLC6A3PDE4BPDE4DADORA3 | |
| SCHEMBL8022478 | 0.83 | ATM (0.46) | ATMCNR1SLC6A3PDE4BPDE4D | |
| SCHEMBL4008874 | 0.81 | ATM (0.50) | ATMCNR1SLC6A3PDE4BPDE4D | |
| SCHEMBL4010086 | 0.79 | ATM (0.46) | ATMCNR1ADORA3MEN1KMT2A | |
| SCHEMBL4009793 | 0.77 | NR1H4 (0.37) | ATMCNR1PDE4BPDE4DNAMPT | |
| SCHEMBL4006533 | 0.75 | PDE4B (0.39) | SLC6A3PDE4BPDE4DADORA3RAB9A | |
| SCHEMBL8033148 | 0.74 | SLC6A3 (0.48) | SLC6A3PDE4BPDE4DMEN1KMT2A | |
| SCHEMBL4009408 | 0.73 | DHPS (0.39) | CNR1PDE4BPDE4DADORA3SMN1; SMN2 | |
| SCHEMBL8031484 | 0.72 | SLC6A3 (0.42) | CNR1SLC6A3PDE4BPDE4DIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |