Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009408 | 0.90 | DHPS (0.39) | DHPSCNR1NAMPTPDE4BPDE4D | |
| SCHEMBL4014816 | 0.84 | ATM (0.45) | DHPSCNR1SLC6A3IDO1NAMPT | |
| SCHEMBL8040909 | 0.83 | CNR1 (0.43) | DHPSCNR1SLC6A3NAMPTPDE4B | |
| SCHEMBL4009406 | 0.81 | FABP4 (0.42) | DHPSCNR1NAMPTPDE4BPDE4D | |
| SCHEMBL4006533 | 0.81 | PDE4B (0.39) | DHPSSLC6A3NAMPTPDE4BPDE4D | |
| SCHEMBL4009793 | 0.78 | NR1H4 (0.37) | DHPSCNR1NAMPTPDE4BPDE4D | |
| SCHEMBL8031734 | 0.74 | SLC6A3 (0.44) | CNR1SLC6A3IDO1NAMPTPDE4B | |
| SCHEMBL4008876 | 0.74 | ATM (0.48) | CNR1SLC6A3NAMPTPDE4BPDE4D | |
| SCHEMBL4014170 | 0.74 | MAPT (0.43) | DHPSNPC1ALDH1A1LMNANFKB1 | |
| SCHEMBL4010263 | 0.73 | DHPS (0.41) | DHPSCNR1NAMPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |