Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | DHPS | P49366 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009408 | 0.91 | DHPS (0.39) | PDE4BPDE4DCYP1A2POLBMAPT | |
| SCHEMBL4009793 | 0.88 | NR1H4 (0.37) | PDE4BPDE4DNAMPTDHPS | |
| SCHEMBL4008876 | 0.84 | ATM (0.48) | PDE4BPDE4DNAMPTRAB9AADORA3 | |
| SCHEMBL4006528 | 0.84 | FABP4 (0.43) | PDE4BPDE4DCYP1A2POLBMAPT | |
| SCHEMBL4014601 | 0.81 | DHPS (0.42) | PDE4BPDE4DNAMPTDHPSRAB9A | |
| SCHEMBL8031734 | 0.80 | SLC6A3 (0.44) | PDE4BPDE4DCYP1A2POLBMAPT | |
| SCHEMBL4011569 | 0.80 | PDE4B (0.36) | PDE4BPDE4DMAPTRAB9AADORA3 | |
| SCHEMBL4007708 | 0.80 | CYP1A2 (0.40) | CYP1A2POLBMAPTNAMPTDHPS | |
| SCHEMBL4008512 | 0.80 | MAPT (0.42) | CYP1A2POLBMAPTDHPSRAB9A | |
| SCHEMBL4009406 | 0.76 | FABP4 (0.42) | PDE4BPDE4DCYP1A2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |