Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.50 |
| ▸ | YAP1 | P46937 | 1/20 | 0.50 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563521 | 0.84 | LMNA (0.68) | LMNACYP1A2CYP2C9CYP2C19TEAD4 | |
| SCHEMBL3812938 | 0.81 | LMNA (0.70) | LMNACYP1A2CYP2C9CYP2C19TEAD4 | |
| Acetic Acid SCHEMBL28343495 | 0.81 | LMNA (0.64) | LMNACYP1A2CYP2C9CYP2C19TEAD4 | |
| SCHEMBL13768445 | 0.80 | ALDH1A1 (0.43) | LMNACYP1A2CYP2C9CYP2C19TEAD4 | |
| SCHEMBL12715082 | 0.79 | LMNA (0.91) | LMNACYP1A2CYP2C9CYP2C19TEAD4 | |
| SCHEMBL3807352 | 0.77 | PDE4D (0.64) | LMNACYP1A2CYP2C9CYP2C19TEAD4 | |
| Ufenamate SCHEMBL36095 | 0.76 | CYP1A2 (0.72) | LMNACYP1A2CYP2C9CYP2C19TEAD4 | |
| Ufenamate SCHEMBL29376700 | 0.76 | CYP1A2 (0.72) | LMNACYP1A2CYP2C9CYP2C19TEAD4 | |
| SCHEMBL10597386 | 0.76 | LMNA (0.71) | LMNACYP1A2CYP2C9CYP2C19TEAD4 | |
| Etofenamate SCHEMBL25152 | 0.76 | LMNA (1.00) | LMNACYP1A2CYP2C9CYP2C19TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | claimed |
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | disclosed |