Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138588 | 0.83 | RXRA (0.33) | — | |
| SCHEMBL16220189 | 0.82 | KDM4E (0.35) | TRPV1APEX1CYP2C19MAPTMAPK1 | |
| SCHEMBL17193433 | 0.82 | APEX1 (0.36) | TRPV1APEX1CYP2C19MAPTMAPK1 | |
| SCHEMBL1138710 | 0.80 | RARA (0.31) | — | |
| SCHEMBL25328676 | 0.79 | APEX1 (0.37) | TRPV1APEX1CYP2C19MAPTMAPK1 | |
| SCHEMBL14059882 | 0.79 | APEX1 (0.39) | TRPV1APEX1CYP2C19MAPTMAPK1 | |
| SCHEMBL31047704 | 0.77 | ALDH1A1 (0.39) | TRPV1APEX1CYP2C19MAPTMAPK1 | |
| SCHEMBL29369689 | 0.77 | ALDH1A1 (0.39) | TRPV1APEX1CYP2C19MAPTMAPK1 | |
| SCHEMBL374980 | 0.77 | ALDH1A1 (0.39) | TRPV1APEX1CYP2C19MAPTMAPK1 | |
| SCHEMBL11983671 | 0.77 | TRPV1 (0.36) | TRPV1APEX1CYP2C19MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579411-B2 | Process for the controlled increase in the molecular weight of polyethylenes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-08-25 | — | — | US | disclosed |
| US-20080146740-A1 | Process for the controlled increase in the molecular weight of polyethylenes | ROTH MICHAEL | 2008-06-19 | — | — | US | disclosed |
| US-7358365-B2 | Process for the controlled increase in the molecular weight of polyethylenes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060128903-A1 | Process for the controlled increase in the molecular weight of polyethylenes | ROTH MICHAEL | 2006-06-15 | — | — | US | disclosed |
| EP-1282630-B1 | Process for Reducing the Molecular Weight of Polypropylene Using Hydroxylamine Esters | CIBA SC HOLDING AG (CH) | 2006-05-10 | — | — | EP | disclosed |
| EP-1655303-A2 | Hydroxylamine esters as polimerization initiators | Ciba SC Holding AG (CH) | 2006-05-10 | — | — | EP | disclosed |
| US-7030196-B2 | Process for reducing the molecular weight of polypropylene | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-04-18 | — | — | US | disclosed |
| US-20030216494-A1 | Hydroxylamine esters as polymerization initiators | CIBA SPECIALTY CHEMICALS CORP. | 2003-11-20 | — | — | US | disclosed |
| EP-1282630-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | Ciba SC Holding AG (CH) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001090113-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-11-29 | — | — | WO | disclosed |
| US-5496921-A | Melt process for polycarbonate with improved heat stability | GE PLASTICS JAPAN (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5484875-A | Copolymeric polycarbonate production method | GE PLASTICS JAPAN (JP) | 1996-01-16 | — | — | US | disclosed |
| US-5470938-A | Copolymeric polycarbonate compositions containing a sulfonic acid compound | GE PLASTICS JAPAN (JP) | 1995-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216494-A1 | Hydroxylamine esters as polymerization initiators | PNMT, HPGDS, HAAO | TRPV1 1642/4885APEX1 231/4885CYP2C19 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.