SCHEMBL720415

SCHEMBL720415

CN1C(=O)C=C(Cc2ccccc2)C1=O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
CALM1 P0DP23 1/20 0.44
PTPN1 P18031 1/20 0.43
TEK Q02763 1/20 0.42
GSK3A P49840 3/20 0.39
GSK3B P49841 3/20 0.39
MGLL Q99685 2/20 0.39
LMNA P02545 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
RGS4 P49798 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
LTA4H P09960 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19155552 0.77 SMN1; SMN2 (0.44) MAOAMAOBGSK3AGSK3BMGLL
SCHEMBL10947340 0.75 RGS4 (0.44) MAOAMAOBCALM1PTPN1TEK
SCHEMBL25280183 0.75 RGS4 (0.47) MAOAMAOBCALM1PTPN1TEK
SCHEMBL29001468 0.73 MAOA (0.41) MAOAMAOBCALM1PTPN1TEK
SCHEMBL2515239 0.69 MAOA (0.69) MAOAMAOBCALM1PTPN1TEK
SCHEMBL23519914 0.68 MGLL (0.33) GSK3AGSK3BMGLLLMNA
SCHEMBL24285588 0.68 GSK3A (0.30) GSK3AGSK3BMGLL
SCHEMBL12246310 0.68 ALDH1A1 (0.54) CALM1TDP1
Diphenylmethane SCHEMBL27450549 0.67 CALM1 (0.86) CALM1LMNALTA4H
SCHEMBL149927 0.67 MAPT (0.53) MAOAMAOBPTPN1LMNARGS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5023339-A Blend with surfactant, protective colloid, and water NIPPON OIL AND FATS CO., LTD. (JP) 1991-06-11 US claimed
US-9150414-B2 Nanocomposite and dispersion comprising the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2015-10-06 US disclosed
US-20120053288-A1 NANOCOMPOSITE AND DISPERSION COMPRISING THE SAME KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2012-03-01 US disclosed
US-6881342-B2 Optically active poly (N-methylbenzylmaleimide), method for its production and its use TOSOH CORPORATION (JP) 2005-04-19 US disclosed
US-6712971-B2 ANIONIC POLYMERIZATION OF (S)-(-)-N-ALPHA-METHYLBENZYL MALEIMIDE IN THE PRESENCE OF AN ASYMMETRIC LIGAND; HIGH SPECIFIC ROTATION AND MOLECULAR WEIGHT TOSOH CORPORATION (JP) 2004-03-30 US disclosed
US-20040030073-A1 Optically active poly (N-methylbenzylmaleimide), method for its production and its use TOSOH CORPORATION 2004-02-12 US disclosed
US-20030149221-A1 Anionic polymerization of (S)-(-)-N-alpha-methylbenzyl maleimide in the presence of an asymmetric ligand; high specific rotation and molecular weight TOSOH CORPORATION 2003-08-07 US disclosed
US-6509478-B2 Having a specific rotation (( alpha )43525) of at least +30 degrees. TOSOH CORPORATION (JP) 2003-01-21 US disclosed
US-20020061994-A1 Optically active poly (N-methylbenzylmaleimide), method for its production and its use TOSOH CORPORATION (JP) 2002-05-23 US disclosed
US-5023339-A Blend with surfactant, protective colloid, and water NIPPON OIL AND FATS CO., LTD. (JP) 1991-06-11 US disclosed