Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | SLC33A1 | O00400 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010015 | 0.90 | PPARG (0.38) | PPARAAGTR1AGTR2PPARGAPLNR | |
| SCHEMBL4011203 | 0.90 | PPARG (0.36) | AGTR1AGTR2PPARGAPLNRSLC33A1 | |
| SCHEMBL1892360 | 0.89 | — | — | |
| SCHEMBL4009738 | 0.83 | AGTR1 (0.37) | AGTR1AGTR2PPARGACHEAPLNR | |
| SCHEMBL1890285 | 0.83 | PPARG (0.38) | PPARGAPLNRFFAR1AKR1B1 | |
| SCHEMBL1892252 | 0.80 | F10 (0.38) | AGTR1PPARGFFAR1AKR1B1 | |
| SCHEMBL4013436 | 0.80 | SLC33A1 (0.40) | SLC33A1 | |
| SCHEMBL1893141 | 0.79 | ACHE (0.40) | ACHEAPLNR | |
| SCHEMBL4167260 | 0.79 | FFAR1 (0.39) | PPARAAGTR1PPARGFFAR1AKR1B1 | |
| SCHEMBL2869467 | 0.79 | APLNR (0.39) | ACHEAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |