Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.64 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31673222 | 1.00 | GRM5 (0.64) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL13907278 | 0.93 | CYP2A6 (0.62) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL3796332 | 0.93 | CYP2A6 (0.67) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL31673242 | 0.88 | CYP2A6 (0.58) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL13907279 | 0.83 | PIK3CA (0.57) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL3835779 | 0.83 | CYP11B2 (0.61) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL4750576 | 0.83 | CYP2A6 (0.53) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL21858038 | 0.83 | CYP2A6 (0.53) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL3837868 | 0.83 | CYP2A6 (0.53) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL1479142 | 0.83 | CYP2A6 (0.53) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1729771-B1 | PYRIDYL DERIVATIVES AND THEIR USE AS MGLU5 RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2009-10-14 | — | — | EP | claimed |
| EP-4570317-A2 | COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | Intervet International B.V. (NL) | 2025-06-18 | — | — | EP | disclosed |
| US-12227485-B2 | Compounds useful for the treatment of infection with Mannheimia haemolytica or Histophilus somni | INTERVET INC. (US) | 2025-02-18 | — | — | US | disclosed |
| US-12157717-B2 | Compounds for the treatment of bovine or swine respiratory disease | INTERVET INC. (US) | 2024-12-03 | — | — | US | disclosed |
| US-12077488-B2 | Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection | INTERVET INC. (US) | 2024-09-03 | — | — | US | disclosed |
| US-20240002415-A1 | PHOSPHINE REAGENTS FOR AZINE FLUOROALKYLATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2024-01-04 | — | — | US | disclosed |
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2023-10-10 | — | — | US | disclosed |
| EP-4232025-A1 | PHOSPHINE REAGENTS FOR AZINE FLUOROALKYLATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3600286-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PARASITIC DISEASES | BROAD INST INC (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-116425607-A | Method for preparing cis-form or trans-form alkene by chromium-catalyzed intermediate alkyne selective hydrogenation | 四川大学 | 2023-07-14 | — | — | CN | disclosed |
| WO-2004018455-A1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |
| WO-2003094830-A2 | NOVEL AZACYCLIC ETHYNYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003082272-A1 | SUBSTITUTED BENZAZOLES AND USE THEREOF AS RAF KINASE INHIBITORS | CHIRON CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |
| EP-0508469-B1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5493024-A | 1,2-DIARYL-2-PROPEN-1-ONE CHEMICAL INTERMEDIATE COMPOUND | DOWELANCO (US) | 1996-02-20 | — | — | US | disclosed |
| US-5374701-A | Crosslinkable polymers of high strength free of structural defects | HAY ALLAN S (CA) | 1994-12-20 | — | — | US | disclosed |
| US-5250532-A | Moths. termites | DOWELANCO (US) | 1993-10-05 | — | — | US | disclosed |
| US-5233046-A | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALLAN S (CA) | 1993-08-03 | — | — | US | disclosed |
| WO-1993009079-A1 | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALAN S (CA) | 1993-05-13 | — | — | WO | disclosed |
| EP-0508469-A1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1992-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12077488-B2 | Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection | SORD, HEXD, SNRPD1 | GRM5 2808/4885CYP2A6 1800/4885CYP2C9 2997/4885 |
| US-12227485-B2 | Compounds useful for the treatment of infection with Mannheimia haemolytica or Histophilus somni | SORD, HEXD, SNRPD1 | GRM5 2971/4885CYP2A6 1800/4885CYP2C9 2317/4885 |
| US-12157717-B2 | Compounds for the treatment of bovine or swine respiratory disease | PIGS, BTD, PPARD | GRM5 2335/4885CYP2A6 1136/4885CYP2C9 2216/4885 |
| US-20240002415-A1 | PHOSPHINE REAGENTS FOR AZINE FLUOROALKYLATION | PTPN3, PHOSPHO1, SKIC3 | GRM5 737/4885CYP2A6 3483/4885CYP2C9 2790/4885 |
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | PTPN3, PHOSPHO1, SKIC3 | GRM5 737/4885CYP2A6 3483/4885CYP2C9 2790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.