Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ABL2 | P42684 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 6/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018745 | 0.94 | CXCR2 (0.35) | SLC6A2SLC6A4SLC6A3MGLLCXCR2 | |
| SCHEMBL4022812 | 0.94 | HTR6 (0.35) | MGLLCXCR2KDM2BHTR6 | |
| SCHEMBL4749224 | 0.92 | OPRM1 (0.35) | MGLLCXCR2OPRM1MEN1KMT2A | |
| SCHEMBL4749242 | 0.92 | OPRM1 (0.35) | MGLLCXCR2OPRM1MEN1KMT2A | |
| SCHEMBL4021646 | 0.85 | MC4R (0.36) | MGLLOPRM1KDM2BMEN1KMT2A | |
| SCHEMBL4751351 | 0.85 | MEN1 (0.40) | MGLLOPRM1MEN1KMT2A | |
| SCHEMBL4752869 | 0.85 | MEN1 (0.40) | MGLLOPRM1MEN1KMT2A | |
| SCHEMBL4025296 | 0.84 | MGLL (0.35) | MGLLKDM2BMEN1KMT2ANPC1 | |
| SCHEMBL4018836 | 0.84 | GRIN1 (0.38) | MGLLKDM2BMEN1KMT2A | |
| SCHEMBL4749392 | 0.83 | MGLL (0.36) | MGLLOPRM1KDM2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |