SCHEMBL9996756

SCHEMBL9996756

C=Cc1ccc(F)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
CCR3 P51677 1/20 0.37
NFE2L2 Q16236 3/20 0.36
TTR P02766 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NPC1 O15118 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HTR2A P28223 2/20 0.35
HTR2C P28335 2/20 0.35
KCNH2 Q12809 1/20 0.35
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11295678 0.84 ALDH1A1 (0.42) ALDH1A1CYP3A4
SCHEMBL16958857 0.82 ALDH1A1 (0.48) ALDH1A1NFE2L2NPC1CYP1A2CYP3A4
SCHEMBL31171177 0.77 TDP1 (0.61) ALDH1A1MAOAMAOBTTRTDP1
SCHEMBL5422596 0.77 MAOA (0.37) MAOAMAOBCCR3NFE2L2TTR
SCHEMBL9996753 0.77 MAOA (0.40) MAOAMAOBCCR3NFE2L2TTR
SCHEMBL96823 0.77 TDP1 (0.61) ALDH1A1MAOAMAOBTTRTDP1
SCHEMBL29376510 0.76 TDP1 (0.60) ALDH1A1TDP1NPC1CYP3A4MAPT
SCHEMBL29413981 0.76 NFE2L2 (0.54) ALDH1A1NFE2L2MAPTRAB9AHTR2A
SCHEMBL319771 0.76 NFE2L2 (0.54) ALDH1A1NFE2L2MAPTRAB9AHTR2A
SCHEMBL109034 0.76 TDP1 (0.60) ALDH1A1TDP1NPC1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127039-B1 HIGH DARKNESS AND HIGH GLOSS DIMENSIONALLY STABLE THERMOPLASTIC SMMA MOLDING COMPOSITION INEOS STYROLUTION GROUP GMBH (DE) 2024-11-20 EP disclosed
EP-4251696-B1 UV RESISTANT SMMA COPOLYMERS WITH LOW HAZE AND HIGH CLARITY INEOS STYROLUTION GROUP GMBH (DE) 2024-11-20 EP disclosed
US-20240317968-A1 HIGH CLARITY AND LOW HAZE UV STABILIZED STYRENE AND METHYL METHACRYLATE COPOLYMERS INEOS STYROLUTION GROUP GMBH (DE) 2024-09-26 US disclosed
CN-118234789-A High clarity, low haze and UV stable styrene-methyl methacrylate copolymers 英力士苯领集团股份公司 2024-06-21 CN disclosed
US-20240010825-A1 UV RESISTANT SMMA COPOLYMERS WITH LOW HAZE AND HIGH CLARITY INEOS STYROLUTION GROUP GMBH (DE) 2024-01-11 US disclosed
EP-4251696-A1 UV RESISTANT SMMA COPOLYMERS WITH LOW HAZE AND HIGH CLARITY INEOS Styrolution Group GmbH (DE) 2023-10-04 EP disclosed
CN-116710517-A Low haze and high clarity anti-UV SMMA copolymers 英力士苯领集团股份公司 2023-09-05 CN disclosed
US-20230183404-A1 HIGH DARKNESS AND HIGH GLOSS DIMENSIONALLY STABLE THERMOPLASTIC SMMA MOLDING COMPOSITION INEOS STYROLUTION GROUP GMBH (DE) 2023-06-15 US disclosed
WO-2023041512-A1 HIGH CLARITY AND LOW HAZE UV STABILIZED STYRENE AND METHYL METHACRYLATE COPOLYMERS INEOS STYROLUTION GROUP GMBH (DE) 2023-03-23 WO disclosed
EP-4127039-A1 HIGH DARKNESS AND HIGH GLOSS DIMENSIONALLY STABLE THERMOPLASTIC SMMA MOLDING COMPOSITION INEOS Styrolution Group GmbH (DE) 2023-02-08 EP disclosed
US-20160355625-A1 METHYL METHACRYLATE VINYLAROMATE COPOLYMERS HSBC CORPORATE TRUSTEE COMPANY (UK) LIMITED (GB) 2016-12-08 US disclosed
US-9249160-B2 Orexin receptor antagonists HEPTARES THERAPEUTICS LIMITED (GB) 2016-02-02 US disclosed
US-9133218-B2 Pesticidally active pyridyl- and pyrimidyl-substituted thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2015-09-15 US disclosed
WO-2015118142-A1 METHYL METHACRYLATE VINYLAROMATE COPOLYMERS STYROLUTION GROUP GMBH (DE) 2015-08-13 WO disclosed
US-20150141423-A1 PESTICIDALLY ACTIVE PYRIDYL- AND PYRIMIDYL- SUBSTITUTED THIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2015-05-21 US disclosed
US-20150126498-A1 OREXIN RECEPTOR ANTAGONISTS NXERA PHARMA UK LIMITED (GB) 2015-05-07 US disclosed
US-8895565-B2 Heterocyclic compound and use of the same NISHIO TETSUYA (JP) 2014-11-25 US disclosed
US-20110319618-A1 HETEROCYCLIC COMPOUND AND USE OF THE SAME NISHIO TETSUYA (JP) 2011-12-29 US disclosed
WO-2007084450-A2 CANNIBINOID RECEPTOR MODULATORS SCHERING CORPORATION (US) 2007-07-26 WO disclosed
US-4001156-A Method of producing epoxy group-containing, quaternary ammonium salt-containing resins PPG INDUSTRIES, INC. (US) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319618-A1 HETEROCYCLIC COMPOUND AND USE OF THE SAME CYP2D6, CYP2B6, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 ALDH1A1 734/4885MAOA 1389/4885MAOB 987/4885
US-20150141423-A1 PESTICIDALLY ACTIVE PYRIDYL- AND PYRIMIDYL- SUBSTITUTED THIAZOLE DERIVATIVES PLPBP, DDT, PIR ALDH1A1 1967/4885MAOA 1032/4885MAOB 739/4885
US-20150126498-A1 OREXIN RECEPTOR ANTAGONISTS HCRTR2, HCRTR1, NPY4R ALDH1A1 3165/4885MAOA 238/4885MAOB 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.