Aminomethylenebisphosphonic Acid

Aminomethylenebisphosphonic Acid

SCHEMBL402218

NC(P(=O)(O)O)P(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 5/20 0.47
LAP3 P28838 4/20 0.47
ERAP2 Q6P179 1/20 0.47
ERAP1 Q9NZ08 1/20 0.41
ALDH1A1 P00352 3/20 0.38
METAP1 P53582 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MMP2 P08253 1/20 0.38
THRB P10828 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ENPEP Q07075 1/20 0.38
GABBR2 O75899 1/20 0.36
GABBR1 Q9UBS5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminomethylenebisphosphonic Acid SCHEMBL9164621 0.96 ANPEP (0.45) ANPEPLAP3ERAP2ERAP1ALDH1A1
Aminomethylenebisphosphonic Acid SCHEMBL11420468 0.93 LAP3 (0.50) ANPEPLAP3ERAP2ERAP1ALDH1A1
Aminomethylenebisphosphonic Acid SCHEMBL7769358 0.87 KDM4E (0.62) ANPEPLAP3ERAP2ERAP1ALDH1A1
Aminomethylenebisphosphonic Acid SCHEMBL1573034 0.84 LAP3 (0.50) ANPEPLAP3ERAP2ERAP1ALDH1A1
Aminomethylenebisphosphonic Acid SCHEMBL9132275 0.84 FDPS (0.41) ANPEPLAP3ERAP2ERAP1ALDH1A1
Aminomethylenebisphosphonic Acid SCHEMBL1245699 0.84 ANPEP (0.38) ANPEPLAP3ERAP2ERAP1ALDH1A1
Aminomethylenebisphosphonic Acid SCHEMBL10355230 0.80 KDM4E (0.53) ANPEPLAP3ERAP2ERAP1ALDH1A1
Aminomethylenebisphosphonic Acid SCHEMBL11025149 0.80 FDPS (0.43) ANPEPLAP3ERAP2ERAP1ALDH1A1
SCHEMBL8973365 0.78
SCHEMBL4104179 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119639250-A Preparation method of red pigment 沈阳化工研究院有限公司 2025-03-18 CN claimed
CN-119439655-A Corrosion-resistant developing solution and preparation method and application thereof 上海戎洲芯科技有限公司 2025-02-14 CN claimed
WO-2024227949-A1 SCREENING AND USES OF GLUTAMINE SYNTHETASE MODULATORS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-11-07 WO claimed
EP-4459280-A1 SCREENING AND USES OF GLUTATHIONE SYNTHETASE MODULATORS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-11-06 EP claimed
CN-118290480-A Water-based zinc-based flow battery electrolyte additive, preparation method and application thereof 绵阳师范学院 2024-07-05 CN claimed
CN-117683226-B Preparation method of quaternary ammonium salt type viscosity reducer containing phosphonic acid groups and viscosity reducer 石家庄市长安育才建材有限公司 2024-05-07 CN claimed
CN-114685779-B Hydrophobic modifier, preparation method thereof and application of hydrophobic modifier in core-shell hybridized nano functional material and cement admixture 南京博特新材料有限公司 2024-03-29 CN claimed
EP-4341359-A1 SCALE INHIBITOR METHODS AND COMPOSITIONS IN SEVERE OPERATING CONDITIONS ChampionX LLC (US) 2024-03-27 EP claimed
CN-117683226-A Preparation method of quaternary ammonium salt type viscosity reducer containing phosphonic acid groups and viscosity reducer 石家庄市长安育才建材有限公司 2024-03-12 CN claimed
CN-117682620-A Pretreatment method of reverse osmosis membrane 杭州锐毅新材料有限公司 2024-03-12 CN claimed
US-4246030-A AMINO ALKYLENE PHOSPHONIC ACID OR ITS DERIVATIVE THE MOGUL CORPORATION (US) 1981-01-20 US claimed
US-4217216-A Corrosion inhibiting compositions THE MOGUL CORPORATION (US) 1980-08-12 US claimed
US-4159901-A AMINOMETHYLENEPHOSPHONIC ACID, THIOL MONSANTO COMPANY (US) 1979-07-03 US claimed
US-4138353-A ANTISCALING AGENTS THE MOGUL CORPORATION (US) 1979-02-06 US claimed
US-4032379-A FILMING AGENTS PHILIP A. HUNT CHEMICAL CORPORATION (US) 1977-06-28 US claimed
US-3985671-A POLYAMINOALKYLENEPHOSPHONATE AND A POLYQUARTERNARY AMMONIUM CHLORIDE UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-10-12 US claimed
US-3969260-A ALKYNYL CYCLOALKANOL, N,N'-DICYCLOALKYL THIOUREA, POLYAMINOMETHYLENEPHOSPHONATE UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-07-13 US claimed
US-3959361-A Process of producing amino methylene phosphonic acids JOH. A. BENCKISER GMBH (DT) 1976-05-25 US claimed
US-3957160-A Process for the prevention of precipitations in water or aqueous solutions HENKEL & CIE G.M.B.H. (DT) 1976-05-18 US claimed
US-3935118-A FATTY ACID, ORGANO-PHOSPHONIC ACID, ALKYLARYL SULFONIC ACID PHILIP A. HUNT CHEMICAL CORPORATION (US) 1976-01-27 US claimed