Aminomethylenebisphosphonic Acid

Aminomethylenebisphosphonic Acid

SCHEMBL7769358

NC(P(=O)(O)O)P(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.62
MMP2 P08253 1/20 0.62
THRB P10828 1/20 0.62
MAPK1 P28482 1/20 0.62
HSD17B10 Q99714 1/20 0.62
ANPEP P15144 5/20 0.46
ERAP2 Q6P179 1/20 0.46
OTC P00480 1/20 0.46
LAP3 P28838 4/20 0.43
GLUL P15104 1/20 0.41
ERAP1 Q9NZ08 1/20 0.40
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
METAP1 P53582 1/20 0.37
ENPEP Q07075 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminomethylenebisphosphonic Acid SCHEMBL10355230 0.92 KDM4E (0.53) KDM4EMMP2THRBMAPK1HSD17B10
Aminomethylenebisphosphonic Acid SCHEMBL11300742 0.87 KDM4E (0.48) KDM4EMMP2THRBMAPK1HSD17B10
Aminomethylenebisphosphonic Acid SCHEMBL402218 0.87 ANPEP (0.47) KDM4EMMP2THRBMAPK1HSD17B10
Aminomethylenebisphosphonic Acid SCHEMBL1573309 0.83 KDM4E (0.43) KDM4EMMP2THRBMAPK1HSD17B10
Aminomethylenebisphosphonic Acid SCHEMBL9164621 0.83 ANPEP (0.45) KDM4EMMP2THRBMAPK1HSD17B10
Aminomethylenebisphosphonic Acid SCHEMBL9497932 0.82 KDM4E (0.42) KDM4EMMP2THRBMAPK1HSD17B10
Etidronic Acid SCHEMBL5163524 0.82 LMNA (0.54) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL28647857 0.81 KDM4E (0.62) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL1921134 0.81 KDM4E (0.62) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL18066158 0.81 KDM4E (0.62) KDM4EMMP2THRBMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694607-B1 Oxidant composition containing stable bleach activator granules CLOROX CO (US) 2001-08-01 EP disclosed
EP-0507475-B1 Detergent composition containing stable bleach activator granules CLOROX CO (US) 1997-05-14 EP disclosed
EP-0694607-A2 Oxidant composition containing stable bleach activator granules The Clorox Company (US) 1996-01-31 EP disclosed
US-5269962-A Oxidant composition containing stable bleach activator granules THE CLOROX COMPANY (US) 1993-12-14 US disclosed
EP-0507475-A2 Detergent composition containing stable bleach activator granules The Clorox Company (US) 1992-10-07 EP disclosed
US-5112514-A Peroxide type bleaches, esterified derivative of acetic acid THE CLOROX COMPANY (US) 1992-05-12 US disclosed
US-5002691-A Esterified-alpha carbon acid formed by perhydrolysis from a hydrogen peroxide source THE CLOROX COMPANY (US) 1991-03-26 US disclosed
EP-0373743-A2 Detergent containing stable bleach activator granules The Clorox Company (US) 1990-06-20 EP disclosed