Aminomethylenebisphosphonic Acid

Aminomethylenebisphosphonic Acid

SCHEMBL1573034

CC(P(=O)(O)O)P(=O)(O)O.CC(P(=O)(O)O)P(=O)(O)O.NC(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 5/20 0.50
ANPEP P15144 6/20 0.44
ERAP1 Q9NZ08 1/20 0.44
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
METAP1 P53582 2/20 0.39
ERAP2 Q6P179 1/20 0.38
FDPS P14324 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminomethylenebisphosphonic Acid SCHEMBL11300742 0.90 KDM4E (0.48) LAP3ANPEPERAP1ALDH1A1TDP1
Methylamine SCHEMBL11796432 0.84 LAP3 (0.50) LAP3ANPEPERAP1ALDH1A1TDP1
Aminomethylenebisphosphonic Acid SCHEMBL11420468 0.84 LAP3 (0.50) LAP3ANPEPERAP1ALDH1A1TDP1
SCHEMBL230835 0.84 LAP3 (0.47) LAP3ANPEPERAP1ALDH1A1TDP1
Aminomethylenebisphosphonic Acid SCHEMBL402218 0.84 ANPEP (0.47) LAP3ANPEPERAP1ALDH1A1TDP1
SCHEMBL9539964 0.81 LAP3 (0.45) LAP3ANPEPERAP1ALDH1A1TDP1
SCHEMBL27852339 0.81 LAP3 (0.45) LAP3ANPEPERAP1ALDH1A1TDP1
SCHEMBL27857546 0.81 LAP3 (0.45) LAP3ANPEPERAP1ALDH1A1TDP1
SCHEMBL22346009 0.81 LAP3 (0.45) LAP3ANPEPERAP1ALDH1A1TDP1
Methyl Alcohol SCHEMBL11367531 0.81 LAP3 (0.45) LAP3ANPEPERAP1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3023520-B1 ENVIRONMENTALLY FRIENDLY GOLD ELECTROPLATING COMPOSITIONS AND CORRESPONDING METHOD ROHM & HAAS ELECT MAT (US) 2019-01-30 EP disclosed
US-20160145756-A1 ENVIRONMENTALLY FRIENDLY GOLD ELECTROPLATING COMPOSITIONS AND METHODS ROHM AND HAAS ELECRONIC MATERIALS LLC 2016-05-26 US disclosed
EP-3023520-A1 ENVIRONMENTALLY FRIENDLY GOLD ELECTROPLATING COMPOSITIONS AND METHODS Rohm and Haas Electronic Materials LLC (US) 2016-05-25 EP disclosed
EP-2109439-B1 OPHTHALMIC COMPOSITIONS WITH A DISUCCINATE BAUSCH & LOMB (US) 2011-04-13 EP disclosed
US-7897553-B2 Ophthalmic compositions comprising polymeric biguanide compositions; used as an antimicrobial component in an ophthalmic lens care solution, or as preservative in pharmaceutical composition or other health care product; good efficacy and lower toxicity BAUSCH & LOMB INCORPORATED (US) 2011-03-01 US disclosed
US-7670997-B2 Ophthalmic compositions comprising a branched, glycerol monoalkyl compound and a fatty acid monoester BAUSCH & LOMB INCORPORATED (US) 2010-03-02 US disclosed
EP-2109439-A1 OPHTHALMIC COMPOSITIONS WITH A DISUCCINATE Bausch & Lomb Incorporated (US) 2009-10-21 EP disclosed
EP-2073800-A2 OPHTHALMIC COMPOSITIONS COMPRISING DIGLYCINE Bausch & Lomb Incorporated (US) 2009-07-01 EP disclosed
WO-2009048860-A1 OPHTHALMIC COMPOSITIONS WITH A DISUCCINATE BAUSCH & LOMB INCORPORATED (US) 2009-04-16 WO disclosed
US-20090092575-A1 OPHTHALMIC COMPOSITIONS WITH A DISUCCINATE BAUSCH & LOMB INCORPORATED 2009-04-09 US disclosed
US-20080095754-A1 OPHTHALMIC COMPOSITIONS COMPRISING DIGLYCINE BAUSCH & LOMB INCORPORATED 2008-04-24 US disclosed
WO-2007146683-A2 OPHTHALMIC COMPOSITIONS COMPRISING A BRANCHED, GLYCEROL MONOALKYL COMPOUND AND A FATTY ACID MONOESTER BAUSCH & LOMB INCORPORATED (US) 2007-12-21 WO disclosed
WO-2007146684-A1 OPHTHALMIC COMPOSITIONS COMPRISING A BRANCHED, GLYCEROL COMPOUND AND A CATIONIC ANTIMICROBIAL BAUSCH & LOMB INCORPORATED (US) 2007-12-21 WO disclosed
US-20070286767-A1 Ophthalmic Compositions Comprising a Branched, Glycerol Monoalkyl Compound and a Fatty Acid Monoester BAUSCH & LOMB PHARMA HOLDINGS CORP. 2007-12-13 US disclosed
US-20070287752-A1 Ophthalmic Compositions Comprising A Branched, Glycerol Compound BAUSCH & LOMB INCORPORATED 2007-12-13 US disclosed
EP-0883407-B1 TREATMENT OF CONTACT LENSES WITH AQUEOUS SOLUTION INCLUDING PHOSPHONIC COMPOUNDS BAUSCH & LOMB (US) 2002-04-24 EP disclosed
US-5858937-A EFFICIENT REMOVAL OF PROTEIN DEPOSITS BAUSCH & LOMB INCORPORATED (US) 1999-01-12 US disclosed
EP-0883407-A1 TREATMENT OF CONTACT LENSES WITH AQUEOUS SOLUTION INCLUDING PHOSPHONIC COMPOUNDS BAUSCH & LOMB INCORPORATED (US) 1998-12-16 EP disclosed
WO-1997031659-A1 TREATMENT OF CONTACT LENSES WITH AQUEOUS SOLUTION INCLUDING PHOSPHONIC COMPOUNDS BAUSCH & LOMB INCORPORATED (US) 1997-09-04 WO disclosed
US-4013586-A Vanadium catalysts prepared with phosphonates MONSANTO COMPANY (US) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070287752-A1 Ophthalmic Compositions Comprising A Branched, Glycerol Compound GK, MGLL, BAK1 LAP3 3720/4885ANPEP 2710/4885ERAP1 4327/4885
US-20080095754-A1 OPHTHALMIC COMPOSITIONS COMPRISING DIGLYCINE MAN1B1, TREH, FUT6 LAP3 1126/4885ANPEP 453/4885ERAP1 181/4885
US-20090092575-A1 OPHTHALMIC COMPOSITIONS WITH A DISUCCINATE ASS1, DEGS1, ODC1 LAP3 4649/4885ANPEP 4435/4885ERAP1 4633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.