Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023022 | 0.81 | MAPT (0.32) | CDK2 | |
| SCHEMBL4023024 | 0.81 | MAPT (0.32) | CDK2 | |
| SCHEMBL4028223 | 0.77 | CDK2 (0.33) | CDK2KCNH2ATMTGFBR1TGFBR2 | |
| SCHEMBL4026141 | 0.73 | MAPK1 (0.35) | CDK2HRH3MEN1KMT2A | |
| SCHEMBL4025418 | 0.73 | HRH3 (0.36) | CDK2HRH3MEN1KMT2A | |
| SCHEMBL5102679 | 0.72 | ALOX15 (0.44) | CDK2HRH3MEN1KMT2A | |
| SCHEMBL6621616 | 0.71 | CDK2 (0.35) | CDK2MEN1KMT2A | |
| SCHEMBL6621622 | 0.71 | CDK2 (0.35) | CDK2MEN1KMT2A | |
| SCHEMBL4030180 | 0.68 | CDK2 (0.46) | CDK2KCNH2 | |
| SCHEMBL1447556 | 0.67 | CDK2 (0.40) | CDK2HRH3ACACBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485375-B1 | PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2009-06-17 | — | — | EP | disclosed |