Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022304 | 0.91 | TAS1R3 (0.39) | MEN1KMT2ASLC6A1TAS1R3TAS1R1 | |
| SCHEMBL4027984 | 0.88 | TAS1R3 (0.37) | MEN1KMT2APOLBTAS1R3TAS1R1 | |
| SCHEMBL4019444 | 0.88 | MC4R (0.35) | KDM2BMEN1KMT2AHSD17B10POLB | |
| SCHEMBL4025103 | 0.86 | KDM2B (0.41) | KDM2BMEN1KMT2ASLC6A1KDM4E | |
| SCHEMBL4019728 | 0.85 | TAS1R3 (0.36) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4022598 | 0.85 | MEN1 (0.35) | KDM2BMEN1KMT2AHSD17B10POLB | |
| SCHEMBL4028155 | 0.82 | KMT2A (0.34) | KDM2BMEN1KMT2ASLC6A1TAS1R3 | |
| SCHEMBL4749432 | 0.82 | CYP2D6 (0.34) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4027216 | 0.81 | KMT2A (0.41) | KDM2BMEN1KMT2AMAPK1MC4R | |
| SCHEMBL4020327 | 0.81 | CPS1 (0.39) | MEN1KMT2APOLBMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |