SCHEMBL4025536

SCHEMBL4025536

CCC(C)OC(=O)CC(O)CC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.52
GPR84 Q9NQS5 4/20 0.41
MAPT P10636 2/20 0.41
GABRR1 P24046 2/20 0.40
LMNA P02545 1/20 0.40
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP9 P14780 1/20 0.37
MMP13 P45452 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6153342 0.92 MMP1 (0.38) SLC22A6MAPTLMNAMMP1MMP2
SCHEMBL9745593 0.88 MMP1 (0.35) SLC22A6MAPTLMNAMMP1MMP2
SCHEMBL451544 0.86 SLC22A6 (0.39) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL15153935 0.85 GABRP (0.38) SLC22A6GPR84MMP1MMP2MMP3
SCHEMBL15478217 0.84 LMNA (0.36) SLC22A6MAPTLMNAMMP1MMP2
SCHEMBL19821829 0.84 TSHR (0.36) SLC22A6MAPTMMP1MMP2MMP3
SCHEMBL23072789 0.82 GABRR1 (0.43) SLC22A6MAPTGABRR1LMNAMMP1
SCHEMBL6155095 0.82 FAAH (0.36) SLC22A6MAPTMMP1MMP2MMP3
SCHEMBL6154465 0.82 MMP1 (0.32) SLC22A6MAPTMMP1MMP2MMP3
SCHEMBL26363332 0.82 LMNA (0.33) SLC22A6MAPTLMNAMMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111518035-A Rosuvastatin tert-butylamine salt and preparation method thereof 安徽鼎旺医药有限公司 2020-08-11 CN claimed
US-8874019-B2 Image forming method KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2014-10-28 US claimed
US-20130202336-A1 IMAGE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-08-08 US claimed
US-20230323022-A1 POLYESTER AND MOLDED ARTICLE CHANG CHUN PLASTICS CO., LTD. (TW) 2023-10-12 US disclosed
US-11773266-B2 Polymer, molded body, foam, resin composition, and production method for polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-03 US disclosed
US-20230129965-A1 HYDROPHILIC AND OLEOPHOBIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-04-27 US disclosed
CN-106676141-B Enzymatic preparation method of chiral intermediate (S) -3-hydroxy glutaric acid monoester 浙江京新药业股份有限公司 2020-12-08 CN disclosed
CN-111518035-A Rosuvastatin tert-butylamine salt and preparation method thereof 安徽鼎旺医药有限公司 2020-08-11 CN disclosed
US-8874019-B2 Image forming method KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2014-10-28 US disclosed
WO-2014140006-A1 PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF 3-HYDROXY-GLUTARIC ACID MONOESTERS AND USE THEREOF SANDOZ AG (CH) 2014-09-18 WO disclosed
US-20130202336-A1 IMAGE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-08-08 US disclosed
EP-1472228-B1 PROCESS FOR THE MANUFACTURE OF HMG-COA REDUCTASE INHIBITORS NOVARTIS AG (CH) 2009-03-25 EP disclosed
US-20080182873-A1 PROCESS FOR THE MANUFACTURE OF HMG-COA REDUCTASE INHIBITORS ACEMOGLU MURAT 2008-07-31 US disclosed
US-7371865-B2 Process for the manufacture of HMG-CoA reductase inhibitors NOVARTIS PHARMACEUTICALS CORPORATION (US) 2008-05-13 US disclosed
US-20050070605-A1 Process for the manufacture of hmg-coa reductase inhibitors ACEMOGLU MURAT (CH) 2005-03-31 US disclosed
EP-1472228-A1 PROCESS FOR THE MANUFACTURE OF HMG-COA REDUCTASE INHIBITORS Novartis AG (CH) 2004-11-03 EP disclosed
WO-2003064392-A1 PROCESS FOR THE MANUFACTURE OF HMG-COA REDUCTASE INHIBITORS NOVARTIS AG (CH) 2003-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182873-A1 PROCESS FOR THE MANUFACTURE OF HMG-COA REDUCTASE INHIBITORS HMGCR, COASY, DHCR7 SLC22A6 1254/4885GPR84 3272/4885MAPT 2873/4885
US-20050070605-A1 Process for the manufacture of hmg-coa reductase inhibitors HMGCR, COASY, DHCR7 SLC22A6 1254/4885GPR84 3272/4885MAPT 2873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.