SCHEMBL4025957

SCHEMBL4025957

Fc1ccc(-c2ccccn2)cc1C(F)(F)F.Fc1ccc(-c2ccccn2)cc1C(F)(F)F.Fc1ccc(-c2ccccn2)cc1C(F)(F)F.[Ir]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.51
MPL P40238 3/20 0.50
GRM4 Q14833 1/20 0.48
KDM4E B2RXH2 2/20 0.47
PDK2 Q15119 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPK1 P28482 1/20 0.47
RAB9A P51151 1/20 0.47
CYP11B2 P19099 1/20 0.42
TRPV3 Q8NET8 2/20 0.42
KAT6A Q92794 1/20 0.41
CTSS P25774 1/20 0.41
CTSK P43235 1/20 0.41
TRPV1 Q8NER1 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CCR1 P32246 1/20 0.41
CCR5 P51681 1/20 0.41
CCR8 P51685 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30704714 0.98 KMO (0.52) KMOMPLGRM4KDM4EPDK2
SCHEMBL4028551 0.98 KMO (0.52) KMOMPLGRM4KDM4EPDK2
SCHEMBL19072645 0.85 CYP11B2 (0.57) KDM4EPDK2ALDH1A1MAPK1RAB9A
SCHEMBL4023458 0.83 NOTUM (0.52) GRM4PDK2ALDH1A1MAPK1RAB9A
SCHEMBL23743199 0.82 RAB9A (0.74) KMOMPLGRM4KDM4EALDH1A1
SCHEMBL4026680 0.81 NOTUM (0.54) GRM4PDK2ALDH1A1MAPK1RAB9A
SCHEMBL160064 0.79 KDM4E (0.67) KMOKDM4EPDK2ALDH1A1MAPK1
SCHEMBL19072793 0.79 MPL (0.55) KMOMPLCYP11B2TRPV3CTSS
SCHEMBL19072716 0.79 KMO (0.56) KMOMPLCYP11B2TRPV3CTSS
SCHEMBL30671517 0.77 MPL (0.50) KMOMPLCYP11B2TRPV3CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1598879-B1 LUMINESCENCE DEVICE, DISPLAY APPARATUS AND METAL COORDINATION COMPOUND CANON KK (JP) 2015-12-02 EP disclosed
US-7534506-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-7026062-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2006-04-11 US disclosed
EP-1191613-B1 Luminescence device, display apparatus and metal coordination compound CANON KK (JP) 2006-03-29 EP disclosed
US-20060014047-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2006-01-19 US disclosed
EP-1598879-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-11-23 EP disclosed
US-20050014025-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-01-20 US disclosed
US-6815091-B2 IRIDIUM, RHODIUM, OR PALLADIUM-PHENYLPYRIDINE COMPLEX WITH SPECIFIED SUBSTITUENT(S); HIGH-EFFICIENCY LUMINESCENCE, HIGH BRIGHTNESS FOR A LONG TIME WHILE MINIMIZING DETERIORATION IN LUMINESCENCE IN ENERGIZED STATE CANON KABUSHIKI KAISHA (JP) 2004-11-09 US disclosed
US-20020064681-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-05-30 US disclosed
EP-1191613-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014047-A1 Luminescence device, display apparatus and metal coordination compound SOD1, ICOSLG, CCRL2 KMO 1493/4885MPL 1249/4885GRM4 1355/4885
US-20020064681-A1 Luminescence device, display apparatus and metal coordination compound CDYL, ZC3HAV1L, ICOSLG KMO 305/4885MPL 588/4885GRM4 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.