Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.39 |
| ▸ | IDH2 | P48735 | 4/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026747 | 0.80 | FABP4 (0.41) | FABP4IDH2IRAK4FABP5GRIK1 | |
| SCHEMBL4033425 | 0.69 | TDP1 (0.42) | HPGDHTTL3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL4030948 | 0.69 | CHRM3 (0.40) | GAAL3MBTL1KDM4EALDH1A1NPSR1 | |
| SCHEMBL4028060 | 0.68 | TDP1 (0.39) | HPGDL3MBTL1KDM4EALDH1A1NPSR1 | |
| SCHEMBL11160989 | 0.68 | FABP4 (0.52) | FABP4IDH2IRAK4FABP5SERPINE1 | |
| SCHEMBL5213164 | 0.66 | KDM4E (0.59) | FABP4IDH2IRAK4FABP5GRIK1 | |
| SCHEMBL4029697 | 0.65 | CHRM3 (0.43) | L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL5099112 | 0.65 | FABP4 (0.62) | FABP4IDH2IRAK4FABP5GRIK1 | |
| SCHEMBL5735479 | 0.65 | ALDH1A1 (0.51) | IRAK4S1PR1S1PR3HTTL3MBTL1 | |
| SCHEMBL4031020 | 0.63 | TAS2R14 (0.36) | FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | claimed |