Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038042 | 0.82 | PTAFR (0.36) | MEN1KMT2AMMP12NAMPT | |
| SCHEMBL5108741 | 0.77 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL4032509 | 0.77 | MMP12 (0.33) | MMP12NAMPTNPSR1 | |
| SCHEMBL19444397 | 0.74 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL18995127 | 0.73 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL5115647 | 0.73 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL23633151 | 0.73 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL20099913 | 0.73 | HRH3 (0.47) | ALDH1A1KDM4ENPC1RAB9ATSHR | |
| SCHEMBL11198582 | 0.72 | LIPG (0.49) | L3MBTL1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29593270 | 0.71 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613613-A4 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2009-03-25 | — | — | EP | disclosed |
| EP-1613613-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091518-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2004-10-28 | — | — | WO | disclosed |