Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028795 | 0.86 | ERCC1 (0.39) | ERCC1FEN1ERCC4ALDH1A1MAPT | |
| SCHEMBL4027681 | 0.84 | ERCC1 (0.41) | ERCC1FEN1ERCC4ALDH1A1MAPT | |
| SCHEMBL4029257 | 0.84 | FEN1 (0.44) | ERCC1FEN1ERCC4ALDH1A1MAPT | |
| SCHEMBL4028964 | 0.82 | FEN1 (0.59) | ERCC1FEN1ERCC4ALDH1A1MAPT | |
| SCHEMBL4028019 | 0.81 | FEN1 (0.39) | ERCC1FEN1ERCC4 | |
| SCHEMBL4031769 | 0.80 | FEN1 (0.38) | ERCC1FEN1ERCC4ALDH1A1MAPT | |
| SCHEMBL4029963 | 0.80 | ERCC1 (0.45) | ERCC1FEN1ERCC4ALDH1A1MAPT | |
| SCHEMBL4026147 | 0.78 | FEN1 (0.39) | ERCC1FEN1ERCC4ALDH1A1 | |
| SCHEMBL4028118 | 0.76 | ERCC1 (0.40) | ERCC1FEN1ERCC4ALDH1A1HPGD | |
| SCHEMBL4032043 | 0.76 | ERCC1 (0.67) | ERCC1FEN1ERCC4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | claimed |