Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026082 | 0.88 | ERCC1 (0.46) | RAB9ANPC1ENPP2ALDH1A1TP53 | |
| SCHEMBL4031044 | 0.82 | NTRK1 (0.41) | ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL4031565 | 0.82 | CXCR2 (0.39) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL4028019 | 0.80 | FEN1 (0.39) | HSD17B10 | |
| SCHEMBL4033336 | 0.79 | ACKR3 (0.39) | RAB9ANPC1ENPP2ALDH1A1TP53 | |
| SCHEMBL4027166 | 0.79 | MEN1 (0.37) | ALDH1A1 | |
| SCHEMBL4026226 | 0.77 | MAOB (0.38) | ALDH1A1SMN1; SMN2TSHRHSD17B10MAPT | |
| SCHEMBL4027676 | 0.75 | MAPK8 (0.40) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL4026962 | 0.75 | F2 (0.39) | ALDH1A1HPGDKDM4E | |
| SCHEMBL4028369 | 0.75 | MEN1 (0.43) | RAB9ANPC1ALDH1A1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | claimed |