Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026959 | 0.86 | ERCC1 (0.51) | F2PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL4028226 | 0.83 | MAPK10 (0.42) | ALDH1A1HPGD | |
| SCHEMBL4028019 | 0.80 | FEN1 (0.39) | — | |
| SCHEMBL4031565 | 0.79 | CXCR2 (0.39) | ALDH1A1 | |
| SCHEMBL4024448 | 0.79 | F2 (0.39) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL4026147 | 0.79 | FEN1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL4034538 | 0.78 | ERCC1 (0.35) | KDM4E | |
| SCHEMBL4034580 | 0.77 | LTB4R (0.39) | — | |
| SCHEMBL4026226 | 0.77 | MAOB (0.38) | KDM4EALDH1A1 | |
| SCHEMBL4031044 | 0.76 | NTRK1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | claimed |