Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031565 | 0.89 | CXCR2 (0.39) | MAPK14POLBMAPTALDH1A1LMNA | |
| SCHEMBL4030887 | 0.86 | ERCC1 (0.51) | NTRK1RETFLT1KDRMAPK14 | |
| SCHEMBL4027166 | 0.85 | MEN1 (0.37) | HTTALDH1A1ERCC1FEN1ERCC4 | |
| SCHEMBL4028019 | 0.84 | FEN1 (0.39) | HSD17B10ERCC1FEN1ERCC4 | |
| SCHEMBL4026648 | 0.83 | NTRK1 (0.44) | NTRK1RETFLT1KDRMAPK14 | |
| SCHEMBL4032051 | 0.82 | RAB9A (0.40) | TSHRHSD17B10MAPTALDH1A1 | |
| SCHEMBL4028505 | 0.79 | ALDH1A1 (0.38) | MAPTHTTALDH1A1ERCC1FEN1 | |
| SCHEMBL4026226 | 0.79 | MAOB (0.38) | TSHRHSD17B10MAPTHTTALDH1A1 | |
| SCHEMBL4027676 | 0.78 | MAPK8 (0.40) | HSD17B10MAPTALDH1A1 | |
| SCHEMBL4028369 | 0.78 | MEN1 (0.43) | MAPTHTTALDH1A1ERCC1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | claimed |