Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031565 | 0.87 | CXCR2 (0.39) | MEN1KMT2ALIPGERCC1FEN1 | |
| SCHEMBL4027165 | 0.86 | ERCC1 (0.51) | MEN1KMT2ATRPV1ROCK2ROCK1 | |
| SCHEMBL4031044 | 0.85 | NTRK1 (0.41) | ERCC1FEN1ERCC4HTTALDH1A1 | |
| SCHEMBL4028019 | 0.84 | FEN1 (0.39) | ERCC1FEN1ERCC4MAPK8MAPK10 | |
| SCHEMBL4026226 | 0.81 | MAOB (0.38) | ERCC1FEN1ERCC4MAPK8MAPK10 | |
| SCHEMBL4028505 | 0.79 | ALDH1A1 (0.38) | ERCC1FEN1ERCC4MAPK8MAPK10 | |
| SCHEMBL4032051 | 0.79 | RAB9A (0.40) | ALDH1A1 | |
| SCHEMBL4028369 | 0.78 | MEN1 (0.43) | MEN1KMT2AERCC1FEN1ERCC4 | |
| SCHEMBL4027676 | 0.77 | MAPK8 (0.40) | MAPK8MAPK10L3MBTL1ALDH1A1 | |
| SCHEMBL4026962 | 0.76 | F2 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | claimed |