Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036678 | 0.92 | CA12 (0.47) | CA12CA1CA2CA9P2RX7 | |
| SCHEMBL4035552 | 0.89 | P2RX7 (0.51) | P2RX7EPHX2 | |
| SCHEMBL4032374 | 0.88 | ALDH1A1 (0.49) | CA12CA1CA2CA9P2RX7 | |
| SCHEMBL4040076 | 0.87 | EPHX2 (0.48) | CA12CA1CA2CA9P2RX7 | |
| SCHEMBL4038551 | 0.87 | MMP1 (0.45) | CA12CA1CA2CA9 | |
| SCHEMBL4035100 | 0.84 | MAPT (0.50) | LMNA | |
| SCHEMBL4033312 | 0.83 | P2RX7 (0.45) | P2RX7EPHX2 | |
| SCHEMBL4032560 | 0.83 | MMP1 (0.43) | — | |
| SCHEMBL4033086 | 0.82 | MMP1 (0.50) | P2RX7EPHX2 | |
| SCHEMBL4038771 | 0.82 | P2RX7 (0.45) | P2RX7LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |