Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036678 | 0.91 | CA12 (0.47) | P2RX7EPHX2 | |
| SCHEMBL4040076 | 0.90 | EPHX2 (0.48) | P2RX7EPHX2 | |
| SCHEMBL4032375 | 0.89 | CA12 (0.46) | P2RX7EPHX2 | |
| SCHEMBL4033312 | 0.89 | P2RX7 (0.45) | P2RX7EPHX2L3MBTL1 | |
| SCHEMBL4033086 | 0.88 | MMP1 (0.50) | P2RX7EPHX2 | |
| SCHEMBL4038771 | 0.88 | P2RX7 (0.45) | P2RX7EPHX2L3MBTL1 | |
| SCHEMBL4038132 | 0.87 | MMP1 (0.44) | P2RX7 | |
| SCHEMBL4035551 | 0.85 | ALDH1A1 (0.56) | P2RX7 | |
| SCHEMBL4034716 | 0.83 | P2RX7 (0.42) | P2RX7EPHX2 | |
| SCHEMBL2441657 | 0.81 | P2RX7 (0.52) | P2RX7EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |